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While men are disproportionally affected by this condition, some women do experience symptoms too. It’s not a life-threatening condition, but chronic pelvic pain syndrome symptoms can severely impact a person’s quality of life and self-esteem.

Daily activities like sex, urination, or even sitting become unbearable. Some men might experience brief and mild pain symptoms, while others will have symptoms that severely affect their overall quality of life.

Neuroplasticity is the brain’s ability to change structurally and functionally with experience and use.


The traditional workaround has been to use binaural beats, which can induce beats in the brain at sub-audio frequencies by manipulating the brain’s response to stereo sound images.

However, the entrainment potential of binaural beats is weak, and requires use of headphones to boot.

Isochronic tones provide all the benefits of binaural beats — while adding some extras of their own.

Broadly, Ann-Maree’s research is understanding the mechanisms that mediate neuroplasticity in the human brain and how altered neuroplasticity contributes to the pathophysiology of disease – in this case chronic pain.

“To date, most chronic pain research focusses on changes in the spinal cord.

The hypothetical halvation time was calculated from the repeat estimates.


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